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[Neuromuscular Disorders in Pregnancy]

Tomoki Suichi1, Sonoko Misawa

  • 1Department of Neurology, Graduate School of Medicine, Chiba University.

Brain and Nerve = Shinkei Kenkyu No Shinpo
|September 11, 2023
PubMed

Women of childbearing age can develop autoimmune or hereditary neuromuscular disorders, which can exacerbate during pregnancy. Stabilizing disease activity during pregnancy has a positive impact on pregnancy and delivery outcomes. Selection of therapeutic agents during pregnancy should be based on the evaluation of the risks and benefits involved. Generally, spontaneous vaginal delivery is recommended; however, preterm and emergency cesarean deliveries may become necessary. Novel agents such as biologics and nucleic acid drugs have been introduced in clinical practice in recent years. These novel agents have provided significant benefit to patients with neuromuscular disorders, although verification of their safety profile in pregnant women is an important issue that should be addressed.

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