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Large-scale Gene Knockdown in C. elegans Using dsRNA Feeding Libraries to Generate Robust Loss-of-function Phenotypes
Published on: September 25, 2013
Expression of the odd-2 Gene in C. elegans
Elizabeth Charnysh1, Keith R Strohmaier2, Joel H Rothman2
1Biology Department, Eastern Connecticut State University, Willimantic, CT, USA.
Abstract:
The odd-2 gene in C. elegans is an orthologue of the odd-skipped gene in Drosophila and the odd-skipped related genes in mammals. The mammalian genes have been shown to be expressed in a variety of tissues and cancers. It was previously reported that ODD-2 is expressed in the intestine and shows some expression outside of the intestine in the tail region. Using a partial ODD-2 ::GFP fusion, we hypothesize that the expression outside of the intestine may be in rectal gland cells, and we also report that ODD-2 may be expressed in the germline sheath cells.

