Topical proactive therapy in dermatology. A scoping review

Area of Science:

• Dermatology
• Clinical Medicine
• Evidence-Based Practice

Background:

• Proactive therapy involves long-term management of clinically intact skin in areas previously affected by disease.
• Initially applied to atopic dermatitis, it aims to sustain remission and reduce exacerbation frequency.
• The goal is to minimize reactive treatments and enhance patient quality of life.

Purpose of the Study:

• To identify dermatological conditions suitable for proactive therapy.
• To evaluate the existing evidence on the efficacy and safety of proactive therapy.
• To identify research gaps in the application of proactive therapy.

Main Methods:

• Scoping review methodology.
• Systematic literature search for studies on proactive therapy in dermatology.
• Synthesis of evidence regarding treatment efficacy and safety.

Main Results:

• Identification of atopic dermatitis as a primary condition for proactive therapy.
• Evidence suggests proactive therapy can maintain remission and reduce exacerbations.
• Further research is needed to confirm efficacy and safety in other dermatological conditions.

Conclusions:

• Proactive therapy is a promising approach for managing relapsing inflammatory skin conditions beyond atopic dermatitis.
• Further research is warranted to establish its role in other dermatological contexts.
• This approach has the potential to significantly improve patient outcomes and quality of life.