Pediatric procedural sedation in African clinical settings: A mixed methods study of African providers' sedation

Megan L Schultz1, Andrew Melby2, Rebecca Gray3

  • 1Department of Pediatrics, Division of Emergency Medicine, Medical College of Wisconsin, Milwaukee, WI, USA.

Insights

Pediatric procedural sedation in Africa is critical but faces barriers. Improving training, resources, and guidelines can enhance safe pediatric sedation practices for children in resource-limited settings.

Area of Science:

  • Pediatric Emergency Medicine
  • Global Health
  • Anesthesiology

Background:

  • Pediatric procedural sedation is vital for emergency care in Africa, yet its practice is poorly understood.
  • This study examines clinical experiences, indications, medications, adverse events, training, and guidelines for pediatric sedation in African resource-limited settings.

Purpose of the Study:

  • To describe current pediatric procedural sedation practices among African medical providers.
  • To identify barriers and challenges to providing safe pediatric sedation in resource-limited African environments.

Main Methods:

  • A mixed-methods approach utilizing semi-structured interviews with key informants across Africa.
  • Purposive sampling ensured representation from diverse geographic, economic, and professional backgrounds in 19 countries.
  • Qualitative and quantitative data were collected on provider practices, barriers, and suggestions for improvement.

Main Results:

  • Thirty-eight key informants reported imaging as the most common indication (42%) and ketamine as the most frequent medication (92%).
  • Hypoxia was the most common adverse event (61%), and only half of providers felt adequately trained.
  • Key barriers identified were lack of resources, insufficient education, and lack of standardization.

Conclusions:

  • Specialized training for pediatric sedation teams is recommended.
  • Developing portable sedation kits and locally relevant guidelines can mitigate barriers.
  • These interventions aim to improve the safety and accessibility of pediatric procedural sedation in resource-limited African settings.
Abstract

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