Related Experiment Video
Updated: Jul 16, 2025
06:41
A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis
Published on: March 9, 2015
9.0K
Impact of Thyroid Dysfunction on Hair Disorders.
Ramadan S Hussein1, Tarek Atia2, Salman Bin Dayel1
1Department of Internal Medicine, Dermatology Unit, College of Medicine, Prince Sattam bin Abdulaziz University, Al-Kharj, SAU.
Cureus
|September 11, 2023
Summary
Thyroid disorders significantly impact hair loss, affecting its prevalence and severity. This review underscores the underestimated connection between thyroid dysfunction and various hair loss conditions, necessitating further research for improved management.
Area of Science:
- Endocrinology
- Dermatology
- Trichology
Background:
- Hair loss affects all demographics and is linked to various risk factors.
- Thyroid hormones (THs) play a crucial role in cellular functions, including those in the skin.
- Thyroid dysfunction, including hyperthyroidism and hypothyroidism, is known to cause hair shedding.
Purpose of the Study:
- To review the impact and prevalence of thyroid disorders on hair loss.
- To enhance understanding of the relationship between thyroid dysfunction and hair disorders.
- To identify knowledge gaps in the diagnosis and management of thyroid-related hair loss.
Main Methods:
- Comprehensive review of scientific articles.
- Inclusion of original research, review articles, and case reports.
- Synthesis of existing literature on thyroid dysfunction and hair loss.
Main Results:
- Thyroid disorders are a significant, often underestimated, cause of hair loss.
- Evidence links thyroid hormones to hair growth regulation and skin health.
- Various thyroid dysfunctions can lead to widespread hair shedding.
Conclusions:
- The prevalence and impact of thyroid disorders on hair loss are frequently underestimated.
- Further research is needed to improve the diagnosis and management of hair loss associated with thyroid dysfunction.
- Understanding the cellular and molecular mechanisms of thyroid dysfunction-related skin diseases is crucial.
Related Concept Videos
01:20Synthesis and Regulation of Thyroid Hormones
4.7K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
4.7K
01:18Functions of Thyroid Hormones
2.8K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
2.8K
01:23The Thyroid Gland
4.0K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
4.0K
01:27Major Hormones and Their Functions
485
Hormones, the biochemical messengers produced by endocrine glands, are pivotal in regulating bodily functions and maintaining homeostasis. Each hormone's balance is crucial; imbalances can lead to significant physiological disruptions. Major hormones include oxytocin, cortisol, epinephrine, estrogen, testosterone, thyroxine, growth hormone, insulin, and glucagon.
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and...
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and...
485
01:27Adrenal Gland Disorders
1.6K
Adrenal gland disorders manifest when the production of adrenal hormones deviates from the norm, resulting in either excessive or insufficient concentrations.
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
1.6K
01:20Accessory Structures of the Skin: Hair Growth and Types
1.4K
Hair growth begins with the production of keratinocytes by the basal cells of the hair bulb. As new cells are deposited at the hair bulb, the hair shaft is pushed through the follicle toward the surface. Keratinization is completed as the cells are pushed to the skin surface to form the shaft of hair that is externally visible. The external hair is completely dead and composed entirely of keratin. Hair can be cut or shaven without damaging the hair structure because the cut is superficial. Most...
1.4K