Lyme Disease Presenting With Interesting Neurological Features of Weakness and Hyporeflexia: A Case Report

Mehak Semy1, Peterkin Lee-Kwen2, Sarfaraz Semy2

  • 1Internal Medicine, Dr. Dnyandeo Yashwantrao (DY) Patil School of Medicine, Mumbai, IND.

Cureus
|September 11, 2023
PubMed

Insights

This case study highlights neuroborreliosis, a Lyme disease complication. Prompt diagnosis and treatment with antibiotics like ceftriaxone and doxycycline are crucial for symptom resolution.

Area of Science:

  • Infectious Diseases
  • Neurology
  • Microbiology

Background:

  • Lyme disease, a tick-borne illness caused by Borrelia spirochetes, presents with diverse clinical manifestations.
  • The disease typically progresses through early localized, early disseminated, and late stages, though atypical presentations occur.
  • Accurate chronological diagnosis is essential for effective management.

Observation:

  • A 25-year-old female presented with progressive numbness and tingling originating in the torso and spreading systemically.
  • Physical examination indicated reduced motor reflexes and strength.
  • Diagnosis of neuroborreliosis with monoradiculitis was confirmed via antibody testing and lumbar puncture.

Findings:

  • The patient's neurological symptoms, including paresthesia and motor deficits, were attributed to neuroborreliosis.
  • Laboratory confirmation was achieved through serological antibody detection and cerebrospinal fluid analysis.
  • Rapid symptom improvement was observed following antibiotic therapy.

Implications:

  • This case underscores the importance of considering neuroborreliosis in patients with unexplained neurological symptoms, even with atypical disease progression.
  • Timely diagnosis and appropriate antibiotic treatment (e.g., ceftriaxone and doxycycline) can lead to rapid recovery.
  • Understanding varied clinical presentations of Lyme disease is vital for clinicians to ensure accurate and efficient patient care.

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