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Related Concept Videos

Appendicitis-II: Diagnostic Studies and Management01:29

Appendicitis-II: Diagnostic Studies and Management

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Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
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Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy01:26

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

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Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
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Endoscopic Procedures II: Colonoscopy01:25

Endoscopic Procedures II: Colonoscopy

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The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections:
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Inflammatory Bowel Disease V: Surgical Management01:21

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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
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Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

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The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
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Assessment of the Rectum and Anus01:25

Assessment of the Rectum and Anus

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Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
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Laparoscopic Management of Para-Caecal Hernia With Small Bowel Obstruction: A Case Report.

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Modeling, Synthesis, and Biological Evaluation of Potential Retinoid X Receptor (RXR)-Selective Agonists: Analogues of 4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic Acid (Bexarotene) and 6-(Ethyl(5,5,8,8-tetrahydronaphthalen-2-yl)amino)nicotinic Acid (NEt-TMN).

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Related Experiment Video

Updated: Jul 16, 2025

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch
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Is It Worth Considering Colonic Evaluation After Appendicectomy?

Ramprasad P Rajebhosale1, Nathan M Robinson2, Nayaab A Kader2

  • 1General and Colorectal Surgery, Colchester General Hospital, East Suffolk and North Essex NHS Foundation Trust, Colchester, GBR.

Cureus
|September 11, 2023
PubMed
Summary
This summary is machine-generated.

Patients over 55 undergoing appendectomy have a higher risk of colorectal cancer. Routine colonoscopies are recommended for this group to detect neoplasms early and improve prognosis.

Keywords:
appendicectomycaecal polypcecal masscolorectal cancercolonoscopy

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Area of Science:

  • Gastroenterology
  • Surgical Oncology
  • Epidemiology

Background:

  • Acute appendicitis can be associated with colorectal cancer, often due to luminal blockage.
  • No national guidelines exist for follow-up of patients over 40 after appendectomy.
  • Early detection of colorectal pathology is crucial to prevent delayed cancer diagnosis.

Purpose of the Study:

  • To determine the prevalence of colorectal cancer and polyps in patients aged 40 and older post-appendectomy.
  • To establish strategies for investigating associated colorectal pathology in acute appendicitis.
  • To prevent delayed diagnosis of colon cancer in this demographic.

Main Methods:

  • Retrospective cohort study of patients aged 40+ undergoing appendectomy (Oct 2011-Oct 2021).
  • Subgroup analysis for age groups 40-54 and 55+.
  • Review of colon investigations (CT pneumocolon, colonoscopy) within 3 years pre/post-appendectomy.
  • Inclusion of colorectal cancers diagnosed within 5 years of appendicitis.

Main Results:

  • 6.63% of patients (51/769) with appendicitis had colorectal neoplasms.
  • 1.04% (8/769) were diagnosed with colorectal cancer, with 0.26% (2/769) being caecal cancer.
  • Patients aged 55+ showed a statistically significant increased risk of caecal pathology (p=0.07).

Conclusions:

  • Patients over 55 with acute appendicitis have an increased risk of significant colorectal neoplasms.
  • Colorectal cancer in this group appears more severe with a poorer prognosis.
  • Routine colonoscopy or CT pneumocolon is recommended for patients over 55 presenting with acute appendicitis or appendiceal neoplasms.