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Related Concept Videos

Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

261
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
261
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

361
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
361
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

161
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
161
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

262
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
262
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

200
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
200

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Related Experiment Video

Updated: Jul 16, 2025

Fluorescence Assays for the Study of Mycobacterium tuberculosis Interaction with the Immune Receptor SLAMF1
07:42

Fluorescence Assays for the Study of Mycobacterium tuberculosis Interaction with the Immune Receptor SLAMF1

Published on: February 28, 2025

396

Mycobacterium tuberculosis-dependent Monocyte Expression Quantitative Trait Loci and Tuberculosis Pathogenesis.

Hyejeong Hong1, Kimberly A Dill-McFarland2, Jason D Simmons2

  • 1Department of Biobehavioral Health Sciences, School of Nursing, University of Pennsylvania, Philadelphia, PA, USA.

Medrxiv : the Preprint Server for Health Sciences
|September 11, 2023
PubMed
Summary

Human myeloid cells have genetically encoded responses to Mycobacterium tuberculosis (Mtb). These Mtb-dependent eQTLs in monocytes influence cytokine expression and resistance to tuberculosis infection.

Keywords:
Mycobacterium tuberculosisexpression quantitative trait locimonocyte responsepro-inflammatory cytokine

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Last Updated: Jul 16, 2025

Fluorescence Assays for the Study of Mycobacterium tuberculosis Interaction with the Immune Receptor SLAMF1
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Fluorescence Assays for the Study of Mycobacterium tuberculosis Interaction with the Immune Receptor SLAMF1

Published on: February 28, 2025

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Preparation of Mycobacterium Tuberculosis Culture Filtrate to Understand TB Pathogenesis
07:32

Preparation of Mycobacterium Tuberculosis Culture Filtrate to Understand TB Pathogenesis

Published on: March 28, 2025

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Area of Science:

  • Immunogenetics
  • Genomics
  • Infectious Disease

Background:

  • Host-pathogen interactions in tuberculosis (TB) are complex, with varied outcomes after Mycobacterium tuberculosis (Mtb) exposure.
  • Human myeloid cells may possess genetically determined responses to Mtb that influence TB pathogenesis.

Conclusions:

  • Monocyte genes harbor Mtb-dependent eQTLs that impact immune responses.
  • These findings offer insights into immunogenetic pathways governing susceptibility to Mtb infection and TB development.