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Surgical Treatment of an Endolymphatic Sac Tumor
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Eustachian tube dysfunction symptoms after endonasal skull base surgery.

David Grimm1, Rachel Daum1,2, Bruna R Castro Silva1

  • 1Department of Otolaryngology-Head & Neck Surgery, Stanford University School of Medicine, Stanford, California, USA.

International Forum of Allergy & Rhinology
|September 11, 2023
PubMed
Summary

A study found that 16% of patients with skull base issues experience Eustachian tube dysfunction (ETD) symptoms. Surgical treatment often improves these symptoms, though some skull base pathologies may worsen ETD.

Keywords:
endoscopic minimally invasive surgery of the skull baseendoscopic skull base surgeryeustachian tube dysfunctionskull base

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Area of Science:

  • Otolaryngology
  • Neurosurgery
  • Skull Base Surgery

Background:

  • Eustachian tube dysfunction (ETD) can significantly impact quality of life.
  • Skull base pathologies present unique challenges for diagnosis and treatment.
  • The relationship between skull base pathology and ETD requires further investigation.

Purpose of the Study:

  • To determine the prevalence of ETD symptoms in patients with skull base pathology.
  • To assess the impact of surgical intervention for skull base pathology on preoperative ETD symptoms.
  • To identify specific skull base pathologies associated with ETD symptom exacerbation.

Main Methods:

  • Retrospective chart review of patients with diagnosed skull base pathology.
  • Preoperative and postoperative assessment of Eustachian tube dysfunction (ETD) symptoms using standardized questionnaires.
  • Correlation analysis between skull base lesion characteristics (location, malignancy) and ETD symptom severity.

Main Results:

  • 16% of patients with skull base pathology reported symptoms of ETD.
  • Significant improvement in ETD symptoms was observed postoperatively in the majority of patients.
  • Central, posterior, or malignant skull base pathologies were associated with a higher incidence or worsening of ETD symptoms.

Conclusions:

  • ETD is a notable comorbidity in patients with skull base pathology.
  • Surgical management of the underlying skull base pathology can effectively alleviate ETD symptoms.
  • Specific tumor locations and malignant characteristics of skull base lesions may predict or exacerbate ETD.