Research progress of CXCR3 inhibitors
1School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Anti-Cancer Drugs
|September 11, 2023
Summary
The CXCR3 receptor is crucial in various diseases, but small molecule inhibitors targeting it have not yet succeeded in clinical trials, indicating a need for further research and development.
Area of Science:
- Immunology
- Pharmacology
- Molecular Biology
Background:
- The CXCR3 receptor, identified in the mid-1990s, is implicated in numerous diseases, including inflammatory, immune, and cardiovascular conditions.
- Its significant role in diverse pathological processes has spurred research into targeted therapeutic strategies.
Conclusions:
- Despite its disease relevance, the therapeutic development of CXCR3 inhibitors faces significant challenges.
- Further research is essential to overcome current limitations and advance CXCR3-targeted therapies.
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