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Published on: November 30, 2022
Ir-Catalyzed B(3)-Amination of o-Carboranes with Amines via Acceptorless Dehydrogenative BH/NH Cross-Coupling
Yik Ki Au1, Qiangqiang Ma1, Jie Zhang1
1Department of Chemistry and State Key Laboratory of Synthetic Chemistry, The Chinese University of Hong Kong Shatin, N.T., Hong Kong, P.R. China.
Abstract:
An efficient and convenient strategy for Ir-catalyzed selective B(3)-amination of o-carboranes with amines via acceptorless BH/NH dehydrocoupling was developed, affording a series of B(3)-aminated-o-carboranes in moderate to high isolated yields with H2 gas as a sole by-product. Such an oxidant-free system endues the protocol sustainability, atom-economy and environmental friendliness. A reaction mechanism via an Ir(I)-Ir(III)-Ir(I) catalytic cycle involving oxidative addition, dehydrogenation and reductive elimination was proposed.
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