Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Altered pattern evoked retinal and cortical potentials associated with human senescence.

G L Trick, L R Trick, K M Haywood

    Current Eye Research
    |October 1, 1986
    PubMed
    Summary

    Aging affects vision by altering neural pathways in the retina and visual cortex. Studies show reduced pattern-reversal visual evoked potentials (PRVEPs) in older adults, indicating age-related neurophysiological changes.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Relative effects of three knowledge of results treatments on coincidence-anticipation performance.

    Journal of motor behavior·2013
    Same author

    Optic disc topography in pseudopapilledema: a comparison to pseudotumor cerebri.

    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society·2002
    Same author

    Quantitative evaluation of papilledema in pseudotumor cerebri.

    Investigative ophthalmology & visual science·1998
    Same author

    Pattern electroretinogram and spatial contrast sensitivity in primary congenital glaucoma.

    Ophthalmology·1997
    Same author

    Pattern electroretinograms and visual evoked potentials in HIV infection: evidence of asymptomatic retinal and postretinal impairment in the absence of infectious retinopathy.

    Neurology·1996
    Same author

    Diabetes can alter the interpretation of visual dysfunction in ocular hypertension.

    Ophthalmology·1996

    Area of Science:

    • Neuroscience
    • Ophthalmology
    • Gerontology

    Background:

    • Healthy elderly individuals often experience visual deficits due to aging.
    • Age-related changes in ocular media and visual pathway neurophysiology contribute to these deficits.
    • While optical changes are known, age-dependent variations in visual neurophysiology remain unclear.

    Purpose of the Study:

    • To investigate age-related alterations in pattern-specific biopotentials from the human retina and visual cortex.
    • To compare neurophysiological responses between young and elderly individuals using visual evoked potentials.

    Main Methods:

    • Simultaneously monitored pattern-reversal visual evoked potentials (PRVEPs) using counterphasing patterns at different rates and sizes.
    • Studied young (20-30 years) and healthy elderly (70-80 years) observers with good visual acuity (≥20/30).

    Related Experiment Videos

  • Corrected data for senile miosis effects on retinal illumination.

    • Main Results:

    • Elderly individuals showed significant variations in biopotential waveform characteristics.
    • Pattern-reversal retinal potentials (PRRP) amplitude was uniformly reduced in the elderly.
    • Pattern-reversal visual evoked potentials (PRVEP) amplitude reductions were also observed, varying with stimulus conditions; no significant latency changes were found.

    Conclusions:

    • Normal aging is associated with alterations in the physiological properties of neural elements in both the retina and visual cortex.
    • Reduced neural signal amplitude, rather than delayed processing, characterizes age-related visual pathway changes.