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Eight-Year Outcomes of Bilateral Lateral Rectus Recessions versus Unilateral Recession-Resection in Childhood
Sean P Donahue1, Danielle L Chandler2, Rui Wu2
1Department of Ophthalmology and Visual Sciences, Vanderbilt University Medical Center, Nashville, Tennessee.
Ophthalmology
|September 11, 2023
Summary
Unilateral recession-resection (R&R) surgery for childhood intermittent exotropia (IXT) showed better long-term outcomes than bilateral lateral rectus recession (BLRc). R&R resulted in higher resolution rates and lower reoperation rates at 8 years.
Area of Science:
- Ophthalmology
- Strabismus Surgery
- Pediatric Eye Care
Background:
- Childhood intermittent exotropia (IXT) is a common strabismus condition.
- Surgical management aims to improve binocular vision and alignment.
- Comparing different surgical techniques is crucial for optimizing long-term outcomes.
Purpose of the Study:
- To compare 8-year outcomes of bilateral lateral rectus recession (BLRc) versus unilateral recession-resection (R&R) for childhood IXT.
- To evaluate the long-term efficacy and safety of these surgical approaches.
Main Methods:
- An 8-year follow-up of a randomized controlled trial (RCT) involving 123 participants with basic-type IXT.
- Participants were children aged 3-11 years with specific exotropia and stereoacuity measurements.
- Outcomes assessed included surgical success, reoperation rates, and changes in alignment and stereoacuity.
Main Results:
- The cumulative probability of suboptimal surgical outcome by 8 years was 68% for BLRc versus 53% for R&R (P=0.08).
- Complete or near-complete resolution at 8 years was achieved in 15% of BLRc patients compared to 37% of R&R patients (P=0.049).
- The cumulative reoperation rate was significantly higher for BLRc (30%) than for R&R (11%) (P=0.049).
Conclusions:
- While the primary outcome showed no statistically significant difference, secondary outcomes favored R&R.
- Unilateral R&R may offer better long-term results than BLRc for basic-type childhood IXT.
- Further investigation into surgical dosing and long-term management strategies is warranted.

