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Updated: Jul 16, 2025

Reverse Yeast Two-hybrid System to Identify Mammalian Nuclear Receptor Residues that Interact with Ligands and/or Antagonists
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The complex biology of aryl hydrocarbon receptor activation in cancer and beyond

Christiane A Opitz1, Pauline Holfelder2, Mirja Tamara Prentzell2

  • 1German Cancer Research Center (DKFZ), Heidelberg, Division of Metabolic Crosstalk in Cancer and the German Cancer Consortium (DKTK), DKFZ Core Center Heidelberg, 69120 Heidelberg, Germany; Neurology Clinic and National Center for Tumor Diseases, 69120 Heidelberg, Germany.

Biochemical Pharmacology
|September 11, 2023
PubMed

Keywords:
AHR activationAHR expressionAHRRARNTCrosstalk with signaling pathwaysDNA methylationDegradation of AHR ligandsEpigenetic regulationInteraction with transcription factorsLigand diversityNon-genomic AHR effectsPosttranslational modifications

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