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Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles
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Machine learning models for predicting pre-eclampsia: a systematic review protocol.

Amene Ranjbar1, Elham Taeidi2, Vahid Mehrnoush2

  • 1Fertility and Infertility Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

BMJ Open
|September 11, 2023
PubMed
Summary
This summary is machine-generated.

This systematic review identifies machine learning predictive factors for pre-eclampsia. It evaluates the diagnostic accuracy of these AI models in predicting pre-eclampsia, a major pregnancy complication.

Keywords:
maternal medicineobstetricsprenatal diagnosis

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Area of Science:

  • Obstetrics and Gynecology
  • Medical Informatics
  • Computational Biology

Background:

  • Pre-eclampsia is a significant global cause of maternal mortality during pregnancy.
  • Identifying predictive factors and accurate diagnostic tools for pre-eclampsia is crucial for improving maternal outcomes.

Purpose of the Study:

  • To systematically review and summarize predictive factors of pre-eclampsia identified through machine learning models.
  • To evaluate the diagnostic accuracy of machine learning models in predicting pre-eclampsia.

Main Methods:

  • Adherence to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.
  • Comprehensive literature search from inception to January 2023 across major databases (PubMed, EMBASE, Scopus, etc.).
  • Inclusion of studies using machine learning for pre-eclampsia prediction; exclusion of non-English and unrelated articles. Risk of bias assessed using PROBAST.

Main Results:

  • The review synthesizes findings on various machine learning algorithms and features used for pre-eclampsia prediction.
  • Diagnostic accuracy metrics (sensitivity, specificity, AUC) of identified models are evaluated.
  • Key predictive factors identified by machine learning models are summarized.

Conclusions:

  • Machine learning models show promise in identifying predictive factors and improving the diagnostic accuracy of pre-eclampsia.
  • Further research and validation of these models are essential for clinical implementation to reduce maternal mortality.