[Ciprofloxacin in Salmonella infection and abdominal typhoid]

Ten patients - two with Salmonella septicaemia associated with AIDS; one each Salmonella excretors in the convalescence stage and with Salmonella osteomyelitis; three with abdominal typhoid, and three with Salmonella enteritis - were treated with the gyrase inhibitor ciprofloxacin. The drug was given for 3-33 days, at a dosage of 250-750 mg orally in most cases. Clinical and bacteriological cure was achieved in nine patients. There were no significant side effects. One patient developed a macular rash, which is within the usual side-effect rate.