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Updated: Jul 16, 2025
An Experimental Paradigm for the Prediction of Post-Operative Pain PPOP
Published on: January 27, 2010
Development of personalized machine learning-based prediction models for short-term postoperative outcomes in
Mert Karabacak1, Konstantinos Margetis2
1Department of Neurosurgery, Mount Sinai Health System, New York, NY, USA.
Purpose:
By predicting short-term postoperative outcomes before surgery, patients undergoing cervical laminoplasty (CLP) surgery could benefit from more accurate patient care strategies that could reduce the likelihood of adverse outcomes. With this study, we developed a series of machine learning (ML) models for predicting short-term postoperative outcomes and integrated them into an open-source online application.
Methods:
National surgical quality improvement program database was utilized to identify individuals who have undergone CLP surgery. The investigated outcomes were prolonged length of stay (LOS), non-home discharges, 30-day readmissions, unplanned reoperations, and major complications. ML models were developed and implemented on a website to predict these three outcomes.
Results:
A total of 1740 patients that underwent CLP were included in the analysis. Performance evaluation indicated that the top-performing models for each outcome were the models built with TabPFN and LightGBM algorithms. The TabPFN models yielded AUROCs of 0.830, 0.847, and 0.858 in predicting non-home discharges, unplanned reoperations, and major complications, respectively. The LightGBM models yielded AUROCs of 0.812 and 0.817 in predicting prolonged LOS, and 30-day readmissions, respectively.
Conclusion:
The potential of ML approaches to predict postoperative outcomes following spine surgery is significant. As the volume of data in spine surgery continues to increase, the development of predictive models as clinically relevant decision-making tools could significantly improve risk assessment and prognosis. Here, we present an accessible predictive model for predicting short-term postoperative outcomes following CLP intended to achieve the stated objectives.
