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Updated: Jul 16, 2025

Psychophysiological Assessment of the Effectiveness of Emotion Regulation Strategies in Childhood
Published on: February 11, 2017
Frustration Response and Regulation Among Irritable Children: Contributions of Chronic Irritability, Internalizing,
Olivia J Derella1,2, Emilie J Butler2, Karen E Seymour3
1Department of Psychiatry and Behavioral Sciences, Montefiore Medical Center/Albert Einstein College of Medicine.
Insights
Childhood chronic irritability (CI) is linked to difficulties in frustration recovery and inhibitory control, especially when co-occurring with internalizing symptoms or ADHD. Addressing self-regulation impairments is key for treatment.
Area of Science:
- Child psychology
- Developmental psychopathology
- Neuroscience
Background:
- Childhood chronic irritability (CI) is associated with significant developmental impairments and comorbidities.
- Frustration reactivity is a known mechanism, but regulation-oriented frustration recovery and cognitive control remain understudied.
- Understanding these factors is crucial for differentiating CI from comorbid conditions.
Purpose of the Study:
- To investigate frustration recovery, tolerance, and cognitive control in children with CI.
- To examine the role of comorbid symptoms, including ADHD and internalizing disorders, in these processes.
- To identify specific self-regulation deficits associated with CI.
Main Methods:
- Sixty-three children (25 with CI, 38 without) and their parents completed surveys.
- Participants underwent computerized tasks: Frustration Go/No-Go (FGNG) and Mirror Tracing Persistence Task (MTPT).
- Analyses compared task performance and affect across groups, including subgroups screened for ADHD.
Main Results:
- Children with CI showed persistent frustration and inhibitory control difficulties during FGNG recovery, not necessarily during initial frustration.
- Internalizing symptoms predicted frustration intolerance and reactivity across tasks.
- ADHD severity correlated with higher frustration reactivity, while oppositional behavior predicted lower frustration. Frustration recovery was linked to lower irritability but higher internalizing symptoms.
Conclusions:
- Co-occurring symptoms, particularly internalizing ones, may explain some frustration-related difficulties in CI.
- Difficulties in post-frustration affect and inhibitory control recovery highlight the importance of self-regulation impairments in characterizing CI.
- These findings suggest that targeting self-regulation deficits could be crucial for managing childhood chronic irritability.
Objective:
The need to understand and treat childhood chronic irritability (CI; i.e. frequent temper loss and angry/irritable mood) is imperative. CI predicts impairment across development and complex comorbidities with both internalizing and externalizing disorders. Research has emphasized frustration reactivity as a key mechanism of CI. However, there are understudied components of frustrative non-reward, particularly regulation-oriented frustration recovery, frustration tolerance, and cognitive control, that may further explain impairments specific to CI beyond comorbid symptoms.
Method:
Sixty-three community children (N = 25 CI/38 non-CI) and a parent completed surveys and the computerized Frustration Go/No-Go (FGNG) and Mirror Tracing Persistence Task (MTPT). Analyses compared task performance and self-rated affect across youth with or without CI, with further comparison based on negative/positive screen for ADHD (N = 45-/18+).
Results:
In mixed effects models assessing change across task, the CI group did not demonstrate more intense frustration on the MTPT or rigged FGNG block but exhibited persisting frustration and inhibitory control difficulties into the FGNG recovery period; the CI+ADHD subgroup drove recovery effects. In GEE and logistic regression models including dimensional symptom clusters, only internalizing symptoms predicted child frustration intolerance and reactivity across tasks. ADHD severity was also associated with higher MTPT frustration reactivity, while oppositional behavior predicted lower frustration. Better frustration recovery was associated with lower irritability, but higher internalizing symptoms.
Conclusions:
Co-occurring symptoms may better explain some frustration-related difficulties among youth with CI. Difficulties with postfrustration affect and inhibitory control recovery suggest the importance of characterizing CI by self-regulation impairments.
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