Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Long-patch Base Excision Repair

Long-patch Base Excision Repair

Since the discovery of the two BER pathways, there has been a debate about how a cell chooses one pathway over the other and the factors determining this selection. Numerous in vitro experiments have pointed out multiple determinants for the sub-pathway selection. These are:

Base Excision Repair

Base Excision Repair

One of the common DNA damages is the chemical alteration of single bases by alkylation, oxidation, or deamination. The altered bases cause mispairing and strand breakage during replication. This type of damage causes minimal change to the DNA double helix structure and can be repaired by the base excision repair (BER) pathways. BER corrects damaged DNA sequences by removing the damaged base and restoring the original base sequence using the complementary strand as a template.
The first step of...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Posterior column osteotomy for spinal realignment in patients with prior lumbar fusion: illustrative case.

Journal of neurosurgery. Case lessons·2025

Same author

Outpatient Neurosurgery: ASCs and the Medicolegal Landscape.

Neurosurgery clinics of North America·2024

Same author

The Importance of Dysphagia Screening Before and After Cervical Spine Fusion.

World neurosurgery·2024

Same author

A comparison of dysphagia rates between long-segment anterior versus posterior cervical fusion.

Journal of neurosurgery. Spine·2024

Same author

Dupilumab as a Therapeutic Approach in Alopecia Universalis.

Cutis·2023

Same author

Nasal reconstructive techniques following Mohs surgery or excisions: a systematic review.

Archives of dermatological research..·2022

Search research articles

Related Experiment Video

Updated: Jul 16, 2025

Single-stage Dynamic Reanimation of the Smile in Irreversible Facial Paralysis by Free Functional Muscle Transfer

Single-stage Dynamic Reanimation of the Smile in Irreversible Facial Paralysis by Free Functional Muscle Transfer

Published on: March 1, 2015

Repair of a Lateral Eyebrow Defect

Michael J Visconti¹, Eileen Axibal²

¹Department of Academic Dermatology, Trinity Health, Ann Arbor, Michigan.

Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [Et Al.]

|September 12, 2023

Summary

No abstract available in PubMed .

More Related Videos

Optic Nerve Transection: A Model of Adult Neuron Apoptosis in the Central Nervous System

Optic Nerve Transection: A Model of Adult Neuron Apoptosis in the Central Nervous System

Published on: May 12, 2011

Establishment of a Severe Dry Eye Model Using Complete Dacryoadenectomy in Rabbits

Establishment of a Severe Dry Eye Model Using Complete Dacryoadenectomy in Rabbits

Published on: January 8, 2020

Related Experiment Videos

Last Updated: Jul 16, 2025

Single-stage Dynamic Reanimation of the Smile in Irreversible Facial Paralysis by Free Functional Muscle Transfer

Single-stage Dynamic Reanimation of the Smile in Irreversible Facial Paralysis by Free Functional Muscle Transfer

Published on: March 1, 2015

Optic Nerve Transection: A Model of Adult Neuron Apoptosis in the Central Nervous System

Optic Nerve Transection: A Model of Adult Neuron Apoptosis in the Central Nervous System

Published on: May 12, 2011

Establishment of a Severe Dry Eye Model Using Complete Dacryoadenectomy in Rabbits

Establishment of a Severe Dry Eye Model Using Complete Dacryoadenectomy in Rabbits

Published on: January 8, 2020