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Related Concept Videos

Treatment for Pulmonary Arterial Hypertension: Endothelin Receptor Antagonists01:18

Treatment for Pulmonary Arterial Hypertension: Endothelin Receptor Antagonists

Endothelins (ETs) are potent vasoactive peptides critical in the human body's various physiological and pathological processes. One of the most promising therapeutic strategies for treating pulmonary arterial hypertension (PAH) involves counteracting the effects of these endothelins using a class of drugs known as endothelin receptor antagonists.
ETs are synthesized through a complex sequence of enzymatic steps, primarily involving an enzyme referred to as endothelin-converting enzyme (ECE). Of...

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Reply to: Huang et al.

Toyoshi Yanagihara1, Kazuya Tsubouchi2, Martin R J Kolb3

  • 1Department of Respiratory Medicine, National Hospital Organization Fukuoka National Hospital, Fukuoka, Japan.

American Journal of Respiratory and Critical Care Medicine
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PubMed
Summary

No abstract available in PubMed .

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