Inadequate gastric preparation and its associated factors for magnetically controlled capsule endoscopy

Area of Science:

• Gastroenterology
• Medical Imaging
• Endoscopy

Background:

• The factors influencing inadequate gastric preparation for magnetically controlled capsule endoscopy (MCE) are not well understood.
• Effective MCE requires optimal visualization of the upper gastrointestinal tract, necessitating clear gastric conditions.

Purpose of the Study:

• To identify factors associated with inadequate gastric preparation before MCE procedures.
• To analyze the impact of medication and timing on gastric cleanliness for MCE.

Main Methods:

• Prospective data collection from 211 patients undergoing MCE between June 2021 and July 2022.
• Gastric cleanliness was assessed using a gastric cleanliness score (GCS) across six stomach regions; adequate preparation was defined as GCS ≥18.
• Logistic regression analysis was employed to determine independent risk factors for inadequate preparation.

Main Results:

• Proton pump inhibitor (PPI) use (OR 3.57) and premedication with simethicone less than 30 minutes prior (OR 2.86) were identified as significant risk factors for inadequate gastric preparation.
• The lower stomach regions exhibited significantly better cleanliness compared to the upper stomach regions (p <0.001).

Conclusions:

• Proton pump inhibitor use and insufficient premedication time (<30 minutes) negatively impact gastric preparation quality for MCE.
• Further research into PPI dosage, duration, and discontinuation timing is warranted.
• Optimizing premedication strategies, including timing and type, is crucial for enhancing overall gastric cleanliness and MCE procedure success.