Right Ventricular Function and Exercise Tolerance in Patients with ST-Elevation Myocardial Infarction
Denisse Guzman-Ramirez1, Anival Trujillo-Garcia1, Meredith Lopez-Rincon1
1Instituto Mexicano del Seguro Social Delegacion Nuevo Leon - Hospital de Cardiologia UMAE - Departamento de Ecocardiografía, Monterrey, Nuevo Leon - México.
Right ventricular dysfunction in ST-segment elevation myocardial infarction patients limits exercise capacity. Cardiac rehabilitation programs may need adjustments for these individuals to improve functional outcomes.
Area of Science:
- Cardiology
- Exercise Physiology
- Rehabilitation Medicine
Background:
- ST-segment elevation myocardial infarction (STEMI) survivors with cardiac dysfunction experience physical activity limitations.
- Right ventricular (RV) function is crucial for enhancing functional capacity post-STEMI.
- Cardiac rehabilitation (CR) is a vital component of recovery for these patients.
Purpose of the Study:
- To investigate the relationship between RV function and exercise tolerance in STEMI patients undergoing CR.
- To determine if pre-CR RV function predicts exercise capacity improvements after CR.
Main Methods:
- Retrospective cohort study of 109 STEMI patients (2019).
- Echocardiographic assessment of RV function prior to a 16-session CR program.
- Cardiopulmonary exercise (CPX) testing performed pre- and post-CR to measure exercise tolerance (peak VO2equivalents).
Main Results:
- 3.7% global, 10.1% radial, and 11% longitudinal RV dysfunction identified.
- Radial and longitudinal RV dysfunction correlated with a lack of cardiorespiratory fitness improvement (p=0.028, p=0.008).
- RV dysfunction (global, longitudinal) was significantly associated with lower initial, final, and improved peak VO2equivalents (p<0.05).
Conclusions:
- Right ventricular dysfunction is linked to reduced exercise capacity in STEMI patients.
- Tailoring or extending CR programs may be beneficial for patients with RV dysfunction.
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