A novel multifunctional fluorescent capillary-based sensor for simultaneous monitoring of pH, O2 and CO2
Xiaohui Wang1, Yuanxiangyi Feng1, Zhe Li1
1Beijing Key laboratory of Work Safety Intelligent Monitoring, School of Electronic Engineering, Beijing University of Posts and Telecommunications, Beijing 100876, China.
Abstract:
A fluorescent capillary sensor for detecting the bioanalytically and biologically relevant analytes pH, O2, and CO2 has been designed. The sensor is based on single capillary tube with 2 mm inner diameter, which is simultaneous doped with emissive O2-sensitive indicator Ru(dpp)3(PF6)2 (RuDP), pH-sensitive and CO2-sensitive indicator 8-hydroxypyrene-1, 3,6-trisulfonic acid trisodium salt (HPTS). The multifunctional sensor can be excited at the same wavelength and realize multi-parameter optical monitoring at the different sensing position. Studies in phosphate-buffered solutions display the excellent feasibility of the capillary sensor for fluorescence detection of pH, O2, and CO2. Overall, the multifunctional capillary sensor exhibits great potential in real-time blood gas analysis, and clinical application of multi-parameter biological detection.
