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Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty
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CROI 2023: Metabolic and Other Complications of HIV Infection

Sudipa Sarkar1, Todd T Brown1

  • 1Johns Hopkins University, Baltimore, Maryland, USA.

Topics in Antiviral Medicine
|September 13, 2023
PubMed

Insights

Comorbidities significantly impact aging individuals with HIV, affecting health and survival. Research at CROI 2023 explored cardiovascular disease, cancer, and obesity, focusing on treatment impacts.

Area of Science:

  • HIV/AIDS research
  • Cardiovascular disease (CVD)
  • Cancer epidemiology
  • Obesity and metabolic disorders

Background:

  • Comorbid conditions significantly affect the health, quality of life, and survival of aging people with HIV.
  • The 2023 Conference on Retroviruses and Opportunistic Infections (CROI) highlighted critical research on comorbidities in this population.

Approach:

  • Review of scientific abstracts presented at CROI 2023 focusing on cardiovascular disease, cancer, and obesity in people with HIV.
  • Analysis of studies investigating contributing factors to CVD, including mental health, antiretroviral therapies (ART), and hormonal pathways.
  • Examination of research on the epidemiology of non-AIDS-defining cancers and the impact of ART on weight gain.

Key Points:

  • CVD research explored links to mental health, ART, and hormonal factors.
  • Epidemiology of non-AIDS-defining cancers in people with HIV was a key focus.
  • Weight gain associated with ART and potential weight reduction after ART discontinuation were significant themes.

Conclusions:

  • CROI 2023 showcased critical advancements in understanding and managing comorbidities in aging people with HIV.
  • The findings have significant clinical implications for improving long-term health outcomes and quality of life.

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