A Comparison of Retrospective ECG-Gated CT and Surgical or Angiographical Findings in Acute Aortic Syndrome
Makoto Orii1, Misato Sone1, Jumpei Fujiwara2
1Department of Radiology, Iwate Medical University.
Insights
Retrospective ECG-gated CT accurately detects intimal tears in aortic dissection and ulcer-like projections in intramural hematoma. Diastolic and systolic phases show similar detection accuracy for these conditions.
Area of Science:
- Cardiovascular Imaging
- Radiology
- Medical Diagnostics
Background:
- Establishing optimal cardiac phases for retrospective ECG-gated CT in aortic pathology is crucial for accurate diagnosis.
- Intimal tears (IT) in aortic dissection (AD) and ulcer-like projections (ULP) in intramural hematoma (IMH) are key indicators requiring precise detection.
- Current literature lacks consensus on the best cardiac phase for identifying these specific findings.
Purpose of the Study:
- To compare the diagnostic accuracy of diastolic-phase versus systolic-phase retrospective ECG-gated CT for detecting IT in AD and ULP in IMH.
- To evaluate the combined utility of both diastolic and systolic phases in improving detection rates.
- To provide evidence-based recommendations for imaging protocols in acute aortic syndromes.
Main Methods:
- Retrospective analysis of 81 patients undergoing emergency ECG-gated CT for AD or IMH.
- Comparison of IT and ULP detection rates using solely diastolic-phase, solely systolic-phase, and combined diastolic-systolic phase imaging.
- Surgical or angiographical confirmation served as the reference standard for accuracy assessment.
Main Results:
- Overall detection accuracy for IT and ULP was high across all methods: 93% (diastolic), 94% (systolic), and 95% (combined).
- No statistically significant differences were observed in detection accuracy among the diastolic-phase, systolic-phase, or combined-phase imaging (P = 0.55).
- Specific analysis for IT in AD and ULP in IMH also revealed no significant differences in accuracy between the cardiac phases.
Conclusions:
- Retrospective ECG-gated CT provides highly accurate detection of intimal tears in aortic dissection and ulcer-like projections in intramural hematoma.
- The choice between diastolic-phase, systolic-phase, or combined-phase imaging does not significantly impact the diagnostic accuracy for these specific findings.
- Current ECG-gated CT protocols are effective for diagnosing critical features of acute aortic syndromes, regardless of the specific cardiac phase utilized.
Abstract:
The best cardiac phases in retrospective ECG-gated CT for detecting an intimal tear (IT) in aortic dissection (AD) and an ulcer-like projection (ULP) in an intramural hematoma (IMH) have not been established. This study aimed to compare the detection accuracy of diastolic-phase and systolic-phase ECG-gated CT for IT in AD and ULP in IMH, with subsequent surgical or angiographical confirmation as the reference standard.In total, 81 patients (67.6 ± 11.8 years; 41 men) who underwent emergency ECG-gated CT and subsequent open surgery or thoracic endovascular aortic repair for AD (n = 52) or IMH (n = 29) were included. The accuracies of detecting IT and ULP were compared among only diastolic-phase, only systolic-phase, and both diastolic-phase and systolic-phase methods of retrospective ECG-gated CT; surgical or angiographical findings were used as the reference standard. The detection accuracy for IT and ULP using only diastolic-phase, only systolic-phase, and both diastolic-phase and systolic-phase methods of ECG-gated CT was 93% [95% CI: 87-97], 94% [95% CI: 88-97], and 95% [95% CI: 90-97], respectively. There were no significant differences in detection accuracy among the 3 acquisition methods (P = 0.55). Similarly, there were no significant differences in the accuracy of detecting IT in AD (P = 0.55) and ULP in IMH (P > 0.99) among only diastolic-phase, only systolic-phase, and both diastolic- and systolic-phase ECG-gated CT.Retrospective ECG-gated CT for detecting IT in AD and ULP in IMH yields highly accurate findings. There were no significant differences seen among only diastolic-phase, only systolic-phase, and both diastolic-phase and systolic-phase ECG-gated CT.
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