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Updated: Jul 16, 2025

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
Published on: October 11, 2018
A comparative study of different variable selection methods based on numerical simulation and empirical analysis
Dake Hou1, Wenli Zhou2, Qiuxia Zhang3
1School of Mathematics, Shandong University, Jinan, China.
Abstract:
This study employs the principles of computer science and statistics to evaluate the efficacy of the linear random effect model, utilizing Lasso variable selection techniques (including Lasso, Elastic-Net, Adaptive-Lasso, and SCAD) through numerical simulation and empirical research. The analysis focuses on the model's consistency in variable selection, prediction accuracy, stability, and efficiency. This study employs a novel approach to assess the consistency of variable selection across models. Specifically, the angle between the actual coefficient vector β and the estimated coefficient vector is computed to determine the degree of consistency. Additionally, the boxplot tool of statistical analysis is utilized to visually represent the distribution of model prediction accuracy data and variable selection consistency. The comparative stability of each model is assessed based on the frequency of outliers. This study conducts comparative experiments of numerical simulation to evaluate a proposed model evaluation method against commonly used analysis methods. The results demonstrate the effectiveness and correctness of the proposed method, highlighting its ability to conveniently analyze the stability and efficiency of each fitting model.
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