Related Experiment Video
Updated: Jul 16, 2025

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis
Published on: March 9, 2018
Congenital pulmonary airway malformation complicated by aspergilloma: A rare adulthood presentation - Case report
Rihab Molah1, Nasser Altowairqi2, Bader Alotaibi2
1College of Medicine, King Saud University, Riyadh, 13315, Saudi Arabia.
Abstract:
Congenital Pulmonary Airway Malformation (CPAM) is an uncommon condition in adults, which typically presents as acute fever and lung abscesses caused by bacterial infections. We present a case of a 39-year-old female with a CPAM in the upper lobe of the right lung, complicated by an aspergilloma, who presented with a history of hemoptysis. The patient underwent an upper lobectomy and is symptom-free in follow-up. 2012 Elsevier Ltd. All rights reserved.
Insights
Congenital Pulmonary Airway Malformation (CPAM) in adults is rare, often presenting with fever and lung abscesses. This case highlights CPAM complicated by aspergilloma, successfully treated with surgery.
Area of Science:
- Pulmonology
- Thoracic Surgery
- Infectious Diseases
Background:
- Congenital Pulmonary Airway Malformation (CPAM) is a rare congenital lung malformation.
- Adult presentation of CPAM is uncommon, often mimicking infectious processes like lung abscesses.
Observation:
- A 39-year-old female presented with hemoptysis, a symptom not typical for uncomplicated CPAM.
- Imaging revealed a CPAM in the right upper lobe complicated by an aspergilloma, a fungal ball within a pre-existing cavity.
Findings:
- The patient had a right upper lobectomy to address the symptomatic CPAM and aspergilloma.
- Post-operative follow-up confirmed the patient is symptom-free, indicating successful surgical management.
Implications:
- This case underscores the importance of considering CPAM in adult patients presenting with respiratory symptoms, even if atypical.
- Surgical resection remains an effective treatment for symptomatic CPAM and associated complications like aspergilloma.
- Early diagnosis and intervention can lead to favorable outcomes in adult CPAM cases.
More Related Videos
15:01Confocal Laser Scanning Microscopy-Based Quantitative Analysis of Aspergillus fumigatus Conidia Distribution in Whole-Mount Optically Cleared Mouse Lung
Published on: September 18, 2021
14:39Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
Published on: November 4, 2010
Related Concept Videos
Other Pulmonary Disorders
Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Asthma-III: Symptoms and Complications
Classification of Asthma
Cystic Fibrosis: Management
Sinus disease and chronic...
Pulmonary Tuberculosis II
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Cystic Fibrosis: Pathogenesis
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation,...