Malignant phyllodes tumour with lymph node metastasis: a diagnostic conundrum resolved by next generation DNA

Related Experiment Video For MED12

Updated: Jul 16, 2025

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
11:15

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors

Published on: September 20, 2016

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Christopher J Schwartz1, Gregor Krings1, Yunn-Yi Chen1

  • 1Department of Pathology, University of California San Francisco (UCSF), San Francisco, CA, USA.

Histopathology
|September 14, 2023
PubMed

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Tumor Progression02:07

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Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
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Keywords:
MED12TERTDNA sequencingmetaplastic carcinomametastasisphyllodes tumour