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Related Experiment Video

Updated: Jul 16, 2025

Indocyanine Green-Guided Intraoperative Imaging to Facilitate Video-Assisted Retroperitoneal Debridement for Treating Acute Necrotizing Pancreatitis

Indocyanine Green-Guided Intraoperative Imaging to Facilitate Video-Assisted Retroperitoneal Debridement for Treating Acute Necrotizing Pancreatitis

Published on: September 8, 2022

Percutaneous Endoscopic Necrosectomy.

Soumya Jagannath Mahapatra¹, Pramod Kumar Garg¹

¹Department of Gastroenterology, All India Institute of Medical Sciences, New Delhi, India.

Gastrointestinal Endoscopy Clinics of North America

|September 14, 2023

Summary

This summary is machine-generated.

Percutaneous endoscopic necrosectomy (PEN) offers a minimally invasive treatment for infected necrotizing pancreatitis. This bedside procedure shows an 80% success rate with few adverse events, providing a vital option for critically ill patients.

Keywords:

Necrosectomy Necrotizing pancreatitis PEN Sinus tract endoscopy

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Area of Science:

Gastroenterology
Minimally Invasive Surgery

Background:

Infected necrotic fluid collections in acute pancreatitis lead to severe morbidity and mortality.
The step-up approach, involving drainage and necrosectomy, is crucial for patients unresponsive to antibiotics.

Purpose of the Study:

To evaluate the efficacy and safety of Percutaneous Endoscopic Necrosectomy (PEN) as a minimally invasive treatment for infected necrotizing pancreatitis.

Main Methods:

PEN utilizes a percutaneous catheter route with a flexible endoscope for necrosectomy.
The procedure can be performed under conscious sedation, even at the bedside for intensive care unit (ICU) patients.
It is particularly suitable for laterally placed infected necrotic fluid collections.

Main Results:

PEN achieved a clinical success rate of 80% in treating infected necrotizing pancreatitis.
The procedure was associated with minimal adverse events.
Its ability to be performed at the bedside benefits critically ill patients.

Conclusions:

Percutaneous endoscopic necrosectomy is an effective and safe minimally invasive option for managing infected necrotizing pancreatitis.
PEN offers a valuable alternative to traditional necrosectomy, especially for specific fluid collection locations and critically ill patients.