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Aptamers: Features, Synthesis and Applications
Aiswarya P U1, Gopika Raj1, Jinju John1
1Bio-organic Laboratory, Department of Chemistry, Sacred Heart College, Kochi, 682013, India.
Chemistry & Biodiversity
|September 14, 2023
Summary
Aptamers offer advantages over antibodies, including heat stability and lower costs, making them valuable tools for biomedical applications like therapeutics and diagnostics. Further modifications can enhance their properties for broader use.
Area of Science:
- Biotechnology
- Molecular Biology
- Biochemistry
Background:
- Aptamers are gaining attention as alternatives to antibodies in scientific research.
- They offer unique advantages such as thermal stability, cost-effectiveness, and versatility.
Purpose of the Study:
- To review the features, applications, and challenges associated with aptamers.
- To highlight the benefits of aptamers compared to antibodies in biomedical fields.
Main Methods:
- Literature review of aptamer research.
- Comparative analysis of aptamers and antibodies.
Main Results:
- Aptamers exhibit unique features beneficial for therapeutics, diagnostics, biosensors, and targeted drug delivery.
- Their properties can be modified to enhance performance and expand applications.
Conclusions:
- Aptamers are promising materials for diverse biomedical applications.
- Ongoing research focuses on optimizing aptamer properties for improved efficacy and broader utilization.
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