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Optimized virtual optical waveguides enhance light throughput in scattering media.

Adithya Pediredla1,2, Matteo Giuseppe Scopelliti3, Srinivasa Narasimhan3

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Ultrasonically-sculpted waveguides confine light in scattering media. Optimized virtual optical waveguides significantly improve light confinement and throughput, validated by experiments.

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Area of Science:

  • Biomedical Optics
  • Acousto-Optics
  • Optical Engineering

Background:

  • Gradient-index optical waveguides can confine light within scattering media.
  • Ultrasound parameters and medium optical properties influence light confinement.
  • Non-invasive light delivery is crucial for various applications, including medical imaging and therapy.

Purpose of the Study:

  • To develop a physically-accurate simulator for ultrasonically-sculpted gradient-index optical waveguides.
  • To quantify the dependencies of light confinement on ultrasound parameters and medium optical properties.
  • To optimize virtual optical waveguides for enhanced light confinement and throughput.

Main Methods:

  • Development of a physically-accurate simulator for virtual optical waveguides.
  • Quantification of light confinement and throughput under varying ultrasound and medium properties.
  • Experimental validation of simulation findings, including light recycling and throughput enhancement.

Main Results:

  • Optimized virtual optical waveguides improve light confinement fourfold at five mean free paths.
  • Virtual optical waveguides enhance light throughput by 50% compared to an external lens in bladder-like tissue at one transport mean free path.
  • Experimental results confirm enhanced light throughput (15%) and light recycling at five transport mean free paths.

Conclusions:

  • Ultrasonically-sculpted gradient-index optical waveguides offer a promising approach for light delivery in scattering media.
  • The developed simulator provides valuable insights for optimizing waveguide performance.
  • Virtual optical waveguides represent a significant advancement for applications requiring precise light control in biological tissues.