Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Contact sensitivity to proflavine.

C L Goh

    International Journal of Dermatology
    |September 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Proflavine lotion can cause allergic contact dermatitis, often unrecognized by patients. This topical antiseptic frequently leads to skin reactions, particularly on the arms and legs.

    Related Concept Videos

    Labeling DNA Probes03:31

    Labeling DNA Probes

    9.1K
    DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
    Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...
    9.1K

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Prevalence and impact of solar lentigines: An international survey.

    Journal of the European Academy of Dermatology and Venereology : JEADV·2026
    Same author

    Patterns of regret for inadequate sun protection: A population-based study [HELIOS].

    Journal of the European Academy of Dermatology and Venereology : JEADV·2026
    Same author

    Attitudes and behaviors regarding sun exposure in Japan compared to Europe and North America.

    The Journal of dermatology·2024
    Same author

    Thirty years of promoting sun safety in France: The messages are heard but not followed!

    Journal of the European Academy of Dermatology and Venereology : JEADV·2023
    Same author

    Do regrets of parents about sun overexposure impact preventive measures applied on their children?

    Journal of the European Academy of Dermatology and Venereology : JEADV·2023
    Same author

    Will digitization, big data and artificial intelligence- and deep learning-based algorithm govern the practice of medicine?

    Journal of the European Academy of Dermatology and Venereology : JEADV·2022

    Area of Science:

    • Dermatology
    • Toxicology
    • Tropical Medicine

    Background:

    • Proflavine lotion is a widely used topical antiseptic in tropical regions.
    • Its potential to cause allergic reactions has been underestimated.
    • Many patients developing dermatitis from proflavine are unaware of the cause.

    Purpose of the Study:

    • To investigate the sensitizing potential of proflavine lotion.
    • To identify clinical presentations of proflavine-induced dermatitis.
    • To assess the prevalence of cross-reactivity with other topical agents.

    Main Methods:

    • A study was conducted on 45 patients presenting with dermatitis.
    • Clinical observations of skin lesions were recorded.
    • Concomitant sensitivity to other substances was evaluated.

    Related Experiment Videos

    Main Results:

    • Most patients presented with acute or subacute dermatitis.
    • Lesions commonly appeared on the arms and legs.
    • 66% of patients showed sensitivity to other medicaments and lanolin.

    Conclusions:

    • Proflavine lotion possesses significant sensitizing potential.
    • Dermatitis from proflavine can manifest acutely or subacutely, often on extremities.
    • Co-existing sensitivities to other topical agents are common in affected individuals.