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Crystal structures of human and mouse ketohexokinase provide a structural basis for species- and isoform-selective

Rebecca Ebenhoch1, Margit Bauer1, Helmut Romig2

  • 1Medicinal Chemistry, Boehringer Ingelheim Pharma GmbH & Co. KG, Birkendorferstrasse 67, 88400 Biberach an der Riss, Germany.

Acta Crystallographica. Section D, Structural Biology
|September 15, 2023
PubMed

Keywords:
fructose metabolismhuman ketohexokinaseinhibitorsisoform selectivitymouse ketohexokinasestructure-based design

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