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Bridging the gap in the symptomatic heart failure patient journey: insights from the Italian scenario
Matteo Ziacchi1, Alberto Spadotto1, Stefano Ghio2
1Cardiology Unit, IRCCS Azienda Ospedaliero Universitaria di Bologna, Bologna, Italy.
Insights
Heart failure management needs remain high, with many patients lacking sufficient treatment options. Cardiac contractility modulation (CCM) offers a potential solution for improving quality of life and functional capacity in heart failure patients.
Area of Science:
- Cardiology
- Heart Failure Management
Background:
- Prognosis for heart failure (HF) patients is poor, characterized by high mortality and reduced quality of life (QOL) and functional status.
- Ongoing HF management needs and patient epidemiology in Italian clinics require exploration, with a focus on cardiac contractility modulation (CCM).
Purpose of the Study:
- To explore the ongoing needs in heart failure (HF) management.
- To investigate the epidemiology of patients followed by Italian HF clinics.
- To assess the role and physician perception of cardiac contractility modulation (CCM) in HF management.
Main Methods:
- Data collected from 14 Italian HF outpatient clinics over 4 weeks.
- Survey distributed to physicians involved in HF management across Italian centers.
- Analysis of patient data and physician responses regarding treatment options and CCM.
Main Results:
- Despite regular follow-up for 94% of patients, 30% receive insufficient therapies.
- Lack of treatment options reported for 23% of symptomatic patients with reduced ejection fraction (EF) and 66% without reduced EF.
- Approximately 3% of the HF population meets criteria for CCM, perceived as useful by 15% of physicians.
Conclusions:
- Cardiac contractility modulation (CCM) could benefit numerous heart failure patients, especially the elderly.
- CCM has the potential to reduce hospitalizations and improve functional capacity and QOL in heart failure patients.
- Despite a small percentage meeting immediate criteria, CCM represents a valuable therapeutic option.
Background:
The prognosis for heart failure (HF) patients remains poor, with a high mortality rate, and a marked reduction in quality of life (QOL) and functional status. This study aims to explore the ongoing needs of HF management and the epidemiology of patients followed by Italian HF clinics, with a specific focus on cardiac contractility modulation (CCM).
Research Design And Methods:
Data from patients admitted to 14 HF outpatients clinics over 4 weeks were collected and compared to the results of a survey open to physicians involved in HF management operating in Italian centers.
Results:
One hundred and five physicians took part in the survey. Despite 94% of patients receive a regular follow-up every 3-6 months, available therapies are considered insufficient in 30% of cases. Physicians reported a lack of treatment options for 23% of symptomatic patients with reduced ejection fraction (EF) and for 66% of those without reduced EF. Approximately 3% of HF population (two patients per month per HF clinic) meets the criteria for immediate CCM treatment, which is considered a useful option by 15% of survey respondents.
Conclusions:
Despite this relatively small percentage, considering total HF population, CCM could potentially benefit numerous HF patients, particularly the elderly, by reducing hospitalizations, improving functional capacity and QOL.
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