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Modular pooled discovery of synthetic knockin sequences to program durable cell therapies

Franziska Blaeschke1, Yan Yi Chen1, Ryan Apathy1

  • 1Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA 94158, USA; Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.

Cell
|September 15, 2023
PubMed
Abstract

Keywords:
CRISPRchimeric antigen receptorchronic stimulationhuman T cellsimmunotherapyknockinspooled screenssynthetic surface receptortranscription factor

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