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Updated: Jul 16, 2025

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation
Published on: January 16, 2019
Lethal complication of a rare cardiac tumor
S Siegel1, L Claus2, T Kamphausen3
1Institut für Rechtsmedizin des Universitätsklinikum Düsseldorf, Moorenstraße 5, 40225, Düsseldorf, Germany. sonja.siegel@med.uni-duesseldorf.de.
Abstract:
Cardiac tumors, especially malignant ones, are rare and diagnosis is challenging since symptoms manifest late and are often non-specific. Achieving a histological diagnosis prior to resection is also difficult because biopsies often fail to yield conclusive results. Due to the low frequency, no standard treatment protocol exists and the prognosis is poor. We present a case of a cardiac sarcoma, which was found during an autopsy performed with regard to medical malpractice, because the patient died due to a medical intervention. To report cases like this is important to gain more knowledge about possible complications regarding rare diseases.
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