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Updated: Jul 16, 2025
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The Left Pneumonectomy Combined with Monocrotaline or Sugen as a Model of Pulmonary Hypertension in Rats
Published on: March 8, 2019
10.8K
[Left pneumonectomy for intrapulmonary unicentric Castleman disease]
Attila Farkas1, Balázs Tolvaj2, Katinka Andrási1
11 Markusovszky Egyetemi Oktatókórház, Mellkassebészeti Osztály Szombathely, Markusovszky u. 5.; 9700 Magyarország.
Orvosi Hetilap
|September 17, 2023
Summary
Castleman disease, a rare lymphoproliferative disorder, can present in the lungs, posing diagnostic challenges. Complete surgical resection offers the best chance for recurrence-free survival in these rare intrapulmonary cases.
Area of Science:
- Thoracic Surgery
- Oncology
- Pathology
Background:
- Castleman disease is a rare lymphoproliferative disorder typically affecting mediastinal lymph nodes.
- Intrapulmonary Castleman disease is exceptionally rare, with limited documented cases.
Observation:
- A 15-year-old female presented with an asymptomatic left-sided lung mass.
- Diagnosis was confirmed as Castleman disease via transthoracic biopsy.
- The tumor involved critical hilar structures, necessitating a left pulmonectomy.
Findings:
- Complete tumor resection (R0) was achieved through left pulmonectomy.
- The patient remained relapse-free for 7 years post-surgery.
- Radical lung resection can be essential for complete tumor removal in rare Castleman disease presentations.
Implications:
- Complete surgical resection is crucial for favorable outcomes in Castleman disease.
- Extended lung resections may be required for intrapulmonary Castleman disease.
- This case highlights the importance of considering Castleman disease in rare lung masses.
