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Updated: Jul 16, 2025

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CRISPR/Cas9 Gene Editing to Make Conditional Mutants of Human Malaria Parasite P. falciparum
Published on: September 18, 2018
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Programming schistosomes - a crisper approach to transgenesis
1Schistosomiasis Laboratory, Rural Health Research Institute, Charles Sturt University, Orange, NSW, Australia.
Trends in Parasitology
|September 17, 2023
Abstract:
Ittiprasert and colleagues identified genomic safe harbour (GSH) sites in Schistosoma mansoni using computational methods and inserted a transgene into one of the sites through clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9-assisted homology-directed repair. This study outlines a promising strategy for functional genomics to study this parasite that causes a debilitating and neglected tropical disease.
Keywords:
CRISPR/Cas9Schistosoma mansonigenome safe harbour sitehomology-directed repairparasitic helminth transgenesisMore Related Videos
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