Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

153
Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
153
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

26
DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
26
Computed Tomography01:10

Computed Tomography

4.6K
Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
4.6K
Positron Emission Tomography01:29

Positron Emission Tomography

4.3K
Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
4.3K
X-ray Imaging01:24

X-ray Imaging

5.6K
German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with...
5.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Feasibility study of image reconstruction for a forceps-type positron emission counter: a simulation-based algorithm comparison.

Physics in medicine and biology·2026
Same author

Visualization of nonlinearity in image reconstruction using nonlocal means filters for regularization under noisy conditions.

Radiological physics and technology·2026
Same author

Sub-0.5-mm Resolution PET Versus Autoradiography: Comparison of mGluR1 Concentrations in Mouse Brain.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2026
Same author

Ultra-dense lutetium oxide ceramic scintillators for positron emission tomography.

Physics in medicine and biology·2026
Same author

Selection of Radiological Physics and Technology Awards 2025.

Radiological physics and technology·2026
Same author

Erratum: Optical imaging for the characterization of radioactive carbon and oxygen ion beams (2019<i>Phys. Med. Biol</i>.<b>64</b>115009).

Physics in medicine and biology·2026

Related Experiment Video

Updated: Jul 16, 2025

Visualization of Low-Level Gamma Radiation Sources Using a Low-Cost, High-Sensitivity, Omnidirectional Compton Camera
06:28

Visualization of Low-Level Gamma Radiation Sources Using a Low-Cost, High-Sensitivity, Omnidirectional Compton Camera

Published on: January 30, 2020

12.6K

Whole Gamma Imaging: Challenges and Opportunities.

Taiga Yamaya1, Hideaki Tashima1, Sodai Takyu1

  • 1Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, 4-9-1 Anagawa, Inage-ku, Chiba 263-8555, Japan.

PET Clinics
|September 17, 2023
PubMed
Summary

Whole gamma imaging (WGI), combining PET and Compton imaging, offers a novel nuclear medicine approach. This technology shows promise for sensitive antibody drug imaging and quantitative hypoxia imaging in tumors.

Keywords:
AntibodyCompton cameraMultiple myelomaPETPositroniumWGI

More Related Videos

Evaluation of the Spatial Distribution of &#947;H2AX following Ionizing Radiation
09:28

Evaluation of the Spatial Distribution of γH2AX following Ionizing Radiation

Published on: August 7, 2010

12.7K
Using Synchrotron Radiation Microtomography to Investigate Multi-scale Three-dimensional Microelectronic Packages
08:46

Using Synchrotron Radiation Microtomography to Investigate Multi-scale Three-dimensional Microelectronic Packages

Published on: April 13, 2016

10.1K

Related Experiment Videos

Last Updated: Jul 16, 2025

Visualization of Low-Level Gamma Radiation Sources Using a Low-Cost, High-Sensitivity, Omnidirectional Compton Camera
06:28

Visualization of Low-Level Gamma Radiation Sources Using a Low-Cost, High-Sensitivity, Omnidirectional Compton Camera

Published on: January 30, 2020

12.6K
Evaluation of the Spatial Distribution of &#947;H2AX following Ionizing Radiation
09:28

Evaluation of the Spatial Distribution of γH2AX following Ionizing Radiation

Published on: August 7, 2010

12.7K
Using Synchrotron Radiation Microtomography to Investigate Multi-scale Three-dimensional Microelectronic Packages
08:46

Using Synchrotron Radiation Microtomography to Investigate Multi-scale Three-dimensional Microelectronic Packages

Published on: April 13, 2016

10.1K

Area of Science:

  • Nuclear Medicine
  • Medical Imaging
  • Physics

Background:

  • Compton imaging is a potential nuclear medicine technique alongside SPECT and PET.
  • Whole gamma imaging (WGI) integrates PET and Compton imaging principles.
  • WGI aims to realize the full potential of Compton imaging in medical applications.

Purpose of the Study:

  • To introduce Whole gamma imaging (WGI) as a practical nuclear medicine imaging method.
  • To explore WGI's capability for sensitive antibody drug imaging and quantitative hypoxia imaging.
  • To demonstrate the feasibility of WGI for early tumor detection and treatment monitoring.

Main Methods:

  • Development of a Whole gamma imaging (WGI) prototype.
  • Utilizing positron emitters like 89Zr and 44Sc.
  • Conducting physics experiments and small animal imaging tests.

Main Results:

  • Preliminary demonstration of WGI concepts in physics experiments.
  • Successful small animal imaging tests using the WGI prototype.
  • Validation of WGI's potential for sensitive imaging applications.

Conclusions:

  • Whole gamma imaging (WGI) represents a significant advancement in nuclear medicine.
  • WGI holds promise for highly sensitive antibody drug imaging for early tumor detection.
  • WGI enables quantitative hypoxia imaging for effective tumor treatment strategies.