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Updated: Jul 16, 2025

Fluorescence detection methods for microfluidic droplet platforms
Published on: December 10, 2011
Sequential detection of inflammation-related hypochlorite ions and viscosity with a relay fluorescent probe
Yu-Qing Zhang1, Zhi-Nan Kang1, Jing-Jie Ming1
1School of Life Science and Engineering, School of Chemistry, Southwest Jiaotong University, Chengdu 610031, People's Republic of China. xuhai@my.swjtu.edu.cn.
Abstract:
Based on the correlation between inflammation and reactive oxygen species and viscosity, a fluorescent probe (SWJT-19) was designed for a relay detection of hypochlorite ions and viscosity. The synthesized probe could quickly and selectively detect hypochlorite ions, as well as viscosity of the system effectively. Moreover, the probe had been successfully applied to sequentially detect hypochlorite ions and viscosity in organisms, as well as imaging in mouse inflammation.
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