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Related Experiment Video

Updated: Jul 16, 2025

Genetic Modification and Recombination of Salivary Gland Organ Cultures

Genetic Modification and Recombination of Salivary Gland Organ Cultures

Published on: January 28, 2013

Biomimetic Gland Models with Engineered Stratagems.

Xiang Lin^1,2, Lingyu Sun¹, Minhui Lu¹

¹Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China.

Research (Washington, D.C.)

|September 18, 2023

Summary

Researchers are developing advanced biomimetic gland models using microfluidics and engineered scaffolds. These in vitro models mimic in vivo conditions for applications in disease modeling and personalized medicine.

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Last Updated: Jul 16, 2025

Genetic Modification and Recombination of Salivary Gland Organ Cultures

Genetic Modification and Recombination of Salivary Gland Organ Cultures

Published on: January 28, 2013

Manipulating the Murine Lacrimal Gland

Manipulating the Murine Lacrimal Gland

Published on: November 18, 2014

Engineering Three-dimensional Epithelial Tissues Embedded within Extracellular Matrix

Engineering Three-dimensional Epithelial Tissues Embedded within Extracellular Matrix

Published on: July 10, 2016

Area of Science:

Biomedical Engineering
Cell Biology
Tissue Engineering

Background:

Glands are vital for physiological processes.
Biomimetic in vitro gland models are of significant interest.
Current research focuses on optimizing cell sources and culture techniques.

Purpose of the Study:

To review biomimetic strategies for constructing in vitro gland models.
To highlight the role of microfluidics in gland model development.
To discuss applications of these models in various medical fields.

Main Methods:

Review of biomimetic strategies for gland model construction.
Focus on microfluidic integration for enhanced biomimicry.
Summary of endocrine and exocrine gland models.

Main Results:

Engineered scaffolds and microfluidics enhance biomimetic features.
Microfluidics promotes structure and function development in gland models.
Biomimetic gland models show promise for disease modeling, drug screening, and regenerative medicine.

Conclusions:

Biomimetic gland models offer diverse applications in medicine.
Microfluidics plays a key role in advancing gland model development.
Future perspectives address current challenges in the field.