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Updated: Jul 16, 2025

Isolation of CD133+ Liver Stem Cells for Clonal Expansion
Published on: October 10, 2011
Arouse potential stemness: Intrinsic and acquired stem cell therapeutic strategies for advanced liver diseases
Yisu Song1,2,3, Zhengyang Lu1,3,4, Wenzhi Shu1,3
1Department of Hepatobiliary and Pancreatic Surgery Affiliated Hangzhou First People's Hospital Zhejiang University School of Medicine Hangzhou, Zhejiang, 310006, China.
Abstract:
Liver diseases are a major health issue, and prolonged liver injury always progresses. Advanced liver disorders impair liver regeneration. Millions of patients die yearly worldwide, even with the available treatments of liver transplantation and artificial liver support system. With its abundant cell resources and significant differentiative potential, stem cell therapy is a viable treatment for various disorders and offers hope to patients waiting for orthotopic liver transplantation. Considering such plight, stem cell therapeutic strategies deliver hope to the patients. Moreover, we conclude intrinsic and acquired perspectives based on stem cell sources. The properties and therapeutic uses of these stem cells' specific types or sources were then reviewed. Owing to the recent investigations of the above cells, a safe and effective therapy will emerge for advanced liver diseases soon.
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