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Aging and exocrine pancreatic function.

L Gullo, M Ventrucci, P Naldoni

    Journal of the American Geriatrics Society
    |November 1, 1986
    PubMed
    Summary
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    Aging does not significantly impact exocrine pancreatic function. The fluorescein dilaurate test confirmed normal digestive capacity in healthy elderly individuals, including those over 80.

    Area of Science:

    • Gastroenterology
    • Gerontology
    • Physiology

    Background:

    • Limited data exists on how aging affects exocrine pancreatic function.
    • Understanding pancreatic function in the elderly is crucial for maintaining digestive health.

    Purpose of the Study:

    • To investigate the influence of aging on exocrine pancreatic function.
    • To assess pancreatic function in healthy elderly individuals, including those aged 80 and above.

    Main Methods:

    • Employed the fluorescein dilaurate test (pancreolauryl test), a noninvasive, tubeless method.
    • Studied 60 healthy noninstitutionalized elderly subjects (mean age 78) and 36 younger controls (mean age 36).

    Main Results:

    • All elderly participants exhibited normal results on the fluorescein dilaurate test.

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  • No significant differences in pancreatic function were found between elderly individuals under and over 80 years old.

    • Conclusions:

    • The aging process itself does not substantially impair exocrine pancreatic function.
    • Digestive capacity remains unaffected in healthy elderly individuals due to aging alone.