Biological potential of copper complexes: a review
Jamshaid Ashraf1, Muhammad Asad Riaz2
1Department of Chemistry, University of Gujrat, Gujrat, Pakistan.
Turkish Journal of Chemistry
|September 18, 2023
Summary
Copper complexes show significant potential in medicinal chemistry, exhibiting antimicrobial, antioxidant, enzyme inhibition, and anti-cancer properties. This review highlights their diverse biological activities, filling a gap in comprehensive literature surveys.
Area of Science:
- Medicinal Chemistry
- Inorganic Chemistry
- Coordination Chemistry
Background:
- Inorganic compounds, especially metal-coordinated complexes, are integral to medicinal chemistry.
- Copper complexes have emerged as compounds of significant interest due to their medicinal potential.
- A lack of comprehensive reviews on the biological activities of copper complexes exists in current literature.
Purpose of the Study:
- To provide a comprehensive survey of the diverse biological activities of copper complexes.
- To discuss the remarkable achievements of copper complexes in medicinal applications over recent decades.
Main Methods:
- Literature review of studies on copper complexes published over the past few decades.
- Analysis of reported biological activities, including antimicrobial, antioxidant, enzyme inhibition, and anti-cancer effects.
Main Results:
- Copper complexes demonstrate a wide spectrum of biological activities.
- Significant achievements have been documented for copper complexes as antimicrobial, antioxidant, enzyme inhibitors, and anti-cancer agents.
- The review consolidates diverse findings on copper complexes' therapeutic potential.
Conclusions:
- Copper complexes represent a promising class of inorganic compounds for drug development.
- Their multifaceted biological activities underscore their importance in medicinal chemistry.
- This review serves as a valuable resource for researchers exploring copper-based therapeutics.
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