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Gd/hafnium oxide@gold@chitosan core-shell nanoparticles as a platform for multimodal theranostics in oncology
Aastha Gupta1, Ritu Singhmar1, Ankur Sood1
1School of Chemical Sciences and Advanced Materials Research Centre, Indian Institute of Technology Mandi, H.P.-175075, India. garima@iitmandi.ac.in.
Abstract:
In the current study, we synthesized thiolated chitosan-stabilized gold-coated, gadolinium-doped hafnium oxide nanoparticles (CAuGH NPs) with the capability of acting as a multifunctional system to deliver anticancer drug doxorubicin (DOX), to enhance radiosensitization by ROS generation, and to provide magnetic resonance (MR) imaging contrast for biomedical applications.
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