Related Experiment Video
Updated: Jul 16, 2025
09:51
Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms
Published on: May 25, 2018
34.0K
Manipulating the Destiny of Wild Populations Using CRISPR
Robyn Raban1, John M Marshall2, Bruce A Hay3
1Department of Cell and Developmental Biology, School of Biological Sciences, University of California, San Diego, La Jolla, California, USA;
Annual Review of Genetics
|September 18, 2023
Summary
Genetic biocontrol uses gene editing technologies like CRISPR to manage pest populations for public health and agriculture. This review examines CRISPR
Area of Science:
- Genetics
- Biotechnology
- Ecology
Background:
- Genetic biocontrol strategies aim to modify or suppress pest populations.
- Genome engineering, particularly CRISPR technology, has accelerated research in this area.
- Applications span public health, agriculture, and biodiversity conservation.
Purpose of the Study:
- To review the current status of CRISPR-based technologies for genetic biocontrol.
- To highlight advancements and persistent challenges in applying these genetic tools to pest management.
Main Methods:
- Literature review of CRISPR applications in genetic biocontrol.
- Analysis of progress in genome engineering for pest suppression.
- Identification of challenges and future directions.
Main Results:
- CRISPR technology is a leading tool in genetic biocontrol research.
- Significant progress has been made in developing CRISPR-based pest control strategies.
- Ethical and technical challenges remain significant.
Conclusions:
- CRISPR offers powerful tools for genetic biocontrol of pests.
- Continued research is needed to overcome challenges for effective and responsible implementation.
- Balancing benefits with potential ecological risks is crucial.
Related Concept Videos
01:59CRISPR
52.2K
Genome editing technologies allow scientists to modify an organism’s DNA via the addition, removal, or rearrangement of genetic material at specific genomic locations. These types of techniques could potentially be used to cure genetic disorders such as hemophilia and sickle cell anemia. One popular and widely used DNA-editing research tool that could lead to safe and effective cures for genetic disorders is the CRISPR-Cas9 system. CRISPR-Cas9 stands for Clustered Regularly Interspaced...
52.2K
01:28CRISPR/Cas9 Genome Editing
48
The CRISPR-Cas system serves as a bacterial defense mechanism against invading genetic elements such as viruses and plasmids, forming the foundation for its adaptation as a powerful genome-editing tool. Originally discovered in prokaryotes, this system has been repurposed to revolutionize genetic engineering across a wide range of organisms, including plants, animals, and humans. The core component, Cas9, is an endonuclease derived from Streptococcus pyogenes, capable of introducing...
48
00:49What is Genetic Engineering?
74.3K
Overview
74.3K
02:53CRISPR and crRNAs
17.1K
Bacteria and archaea are susceptible to viral infections just like eukaryotes; therefore, they have developed a unique adaptive immune system to protect themselves. Clustered regularly interspaced short palindromic repeats and CRISPR-associated proteins (CRISPR-Cas) are present in more than 45% of known bacteria and 90% of known archaea.
The CRISPR-Cas system stores a copy of foreign DNA in the host genome and uses it to identify the foreign DNA upon reinfection. CRISPR-Cas has three different...
The CRISPR-Cas system stores a copy of foreign DNA in the host genome and uses it to identify the foreign DNA upon reinfection. CRISPR-Cas has three different...
17.1K