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Related Experiment Video

Updated: Jul 16, 2025

Author Spotlight: Finding New Therapeutic Targets for Malignant Peripheral Nerve Sheath Tumor Through Genome-Scale shRNA Screens
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Glomangiopericytoma with CTNNB1 mutation.

Shinji Iwata1, Riko Kitazawa2, Sohei Kitazawa2

  • 1Otolaryngology, Ehime Prefectural Niihama Hospital, Niihama, Japan h447033x@mails.cc.ehime-u.ac.jp.

BMJ Case Reports
|September 18, 2023
PubMed
Summary

Glomangiopericytoma, a rare nasal tumor, was diagnosed in an elderly woman. Identifying CTNNB1 mutations was key to confirming the diagnosis of this indolent neoplasm.

Area of Science:

  • Oncology
  • Pathology
  • Otorhinolaryngology

Background:

  • Glomangiopericytoma (GPC) is an exceptionally rare nasal cavity tumor, comprising less than 0.5% of all such neoplasms.
Keywords:
ear, nose and throat/otolaryngologyhead and neck cancerpathology

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  • GPCs are characterized as borderline malignant to indolent and are associated with perivascular myeloid cells.