Related Experiment Video
Updated: Jul 16, 2025
A Standardized Obstacle Course for Assessment of Visual Function in Ultra Low Vision and Artificial Vision
Published on: February 11, 2014
Comprehensive evaluation of functional vision, quality of life, and cognitive ability in pediatric uveitis
Wenjuan Wan1, Zhijun Chen1, Yan Xun1
1The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Lab of Ophthalmology, Chongqing Branch of National Clinical Research Center for Ocular Diseases, Chongqing Eye Institute, Chongqing, P. R. China.
Insights
Pediatric uveitis significantly impacts children's vision, quality of life, and cognitive abilities. Impaired vision in pediatric uveitis hinders functional vision and cognitive development.
Area of Science:
- Ophthalmology
- Pediatrics
- Developmental Psychology
Background:
- Pediatric uveitis can lead to severe vision impairment in children.
- This condition negatively affects quality of life and cognitive development.
Purpose of the Study:
- To evaluate functional vision, quality of life (vision-related and health-related), and cognitive ability in children with uveitis.
Main Methods:
- Children aged 5-16 with uveitis completed validated questionnaires: CVAQC, IVI-C, PedsQL, C-WISC, and HAD.
- Functional vision, vision-related quality of life, health-related quality of life, and cognitive abilities were assessed.
Main Results:
- Pediatric uveitis patients showed significantly lower scores in functional vision (CVAQC), vision-related quality of life (IVI-C), and health-related quality of life (PedsQL).
- Lower IQ scores (full-scale and performance) were observed in patients with poorer best-eye visual acuity.
- Verbal IQ was lower in males with impaired vision; parental education levels were also lower in families with impaired vision.
Conclusions:
- Impaired vision from pediatric uveitis significantly affects children's functional vision and overall quality of life.
- Cognitive development in children with uveitis is substantially hindered by vision impairment.
Background:
Pediatric uveitis may cause severe impairment of vision in children and affect their quality of life as well as cognitive ability. This study aims to evaluate the functional vision, visual-related and health-related quality of life, and cognitive ability in pediatric uveitis.
Methods:
Children with uveitis aged 5-16 years old completed six validated instruments to assess functional visual ability with Cardiff Visual Ability Questionnaire for Children (CVAQC), vision-related quality of life with Impact of Vision Impairment for Children (IVI-C), health-related quality of life with Pediatric Quality of Life Inventory (PedsQL), cognitive ability with Chinese Wechsler Intelligence Scale for Children (C-WISC), and depression and anxiety evaluation with Hospital Anxiety and Depression Scale (HAD).
Results:
The CVAQC, IVI-C, and PedsQL scores of pediatric uveitis were significantly lower than that of normal levels. Full-scale intelligence quotient (IQ) and performance IQ were significantly lower in pediatric uveitis patients with impaired vision in their best eye (visual acuity < 0.3) compared to those with a vision equal to or better than 0.3. Verbal IQ was significantly lower in male pediatric uveitis patients with impaired vision compared to those with a vision equal to or better than 0.3. Additionally, parents of pediatric uveitis patients with impaired vision generally had lower educational levels than parents of those with a vision equal to or better than 0.3.
Conclusions:
Impaired vision caused by pediatric uveitis has a significant impact on children's functional visual ability and quality of life. The development of cognitive function in pediatric uveitis is also significantly hindered.
Related Concept Videos
01:25Glaucoma: Overview
01:22Photoreceptors and Visual Pathways
01:27Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...