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Updated: Jul 16, 2025

Large-Scale SARS-CoV-2 Testing Utilizing Saliva and Transposition Sample Pooling
Published on: June 23, 2022
Collapse transition in epidemic spreading subject to detection with limited resources
Santiago Lamata-Otín1,2, Adriana Reyna-Lara3, David Soriano-Paños2,4
1Department of Condensed Matter Physics, University of Zaragoza, 50009 Zaragoza, Spain.
Abstract:
Compartmental models are the most widely used framework for modeling infectious diseases. These models have been continuously refined to incorporate all the realistic mechanisms that can shape the course of an epidemic outbreak. Building on a compartmental model that accounts for early detection and isolation of infectious individuals through testing, in this article we focus on the viability of detection processes under limited availability of testing resources, and we study how the latter impacts on the detection rate. Our results show that, in addition to the well-known epidemic transition at R_{0}=1, a second transition occurs at R_{0}^{★}>1 pinpointing the collapse of the detection system and, as a consequence, the switch from a regime of mitigation to a regime in which the pathogen spreads freely. We characterize the epidemic phase diagram of the model as a function of the relevant control parameters: the basic reproduction number, the maximum detection capacity of the system, and the fraction of individuals in shelter. Our analysis thus provides a valuable tool for estimating the detection resources and the level of confinement needed to face epidemic outbreaks.
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