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The added value of automated HPC count: detecting clinically important interferences on the flow cytometric CD34+

Alice Brochier1, Mattias Hofmans1, Stijn Lambrecht1

  • 1Hematology Department of Laboratory Medicine, Ghent University Hospital, Ghent, Belgium.

Clinical Chemistry and Laboratory Medicine
|September 19, 2023
PubMed
Abstract

No abstract available in PubMed .

Keywords:
CD34+ stem cell countHPC countXN hematology analyzerhematopoietic stem cell transplant

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The development of flow cytometry techniques began in 1934 with initial attempts by Andrew Moldavan, a bacteriologist who counted the cells in a flowing capillary system. Moldavan pumped cells through a capillary tube focused under a microscope for visualization. The invention of photometry allowed the measurement of differentially-stained cells, and Louis Kamentsky developed the first multiparameter flow cytometer in 1965 to identify and count the cancer cells in cervical tissue specimens.
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